ICAP
AC-XX - Unclassified Patterns
Previous Nomenclature
Description

The AC-XX comprises a group of rare and unusual patterns that have not been fully characterized and, therefore, not included in the current ICAP classification tree. The AC-XX category is an ‘umbrella’ designation that accommodates a variety of these unclassified patterns

Antigen Association Several autoantigens (known and unknown) related with staining of the nucleus, cytoplasm, and mitotic cells.
Clinical Relevance
First level information
About Clinical Relevance & List of Abbreviations
The antigenic identity and clinical relevance of unclassified patterns for most patterns is uncertain. Still, it is important to recognize them to avoid their misclassification as traditional ICAP patterns.
First level information references
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Herold M, Klotz W, Andrade LEC, Conrad K, de Melo Cruvinel W, Damoiseaux J, Fritzler MJ, von Muhlen CA, Satoh M, Chan EKL. International Consensus on Antinuclear Antibody Patterns: defining negative results and reporting unidentified patterns. Clin Chem Lab Med. 2018 Sep 25;56(10):1799-1802.
Second level information
None
Second level information references
None
Last updated in September 2025
FAQ
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Online since 19 May 2015