ICAP
AC-5 - Nuclear large/coarse speckled
Synonym spliceosome/nuclear matrix
Antigen Association hnRNP, U1RNP, Sm, RNA polymerase III
Disease Association MCTD, SLE, SSc
Description Coarse speckles across all nucleoplasm. The nucleoli may be stained or not stained. Mitotic cells (metaphase, anaphase, and telophase) have the chromatin mass not stained. e.g. anti-Sm, anti-U1 RNP
Online since 19 May 2015